Semax
€39,49 – €39,95Price range: €39,49 through €39,95
Semax peptide (MEHFPGP), 5 mg vial, ≥99% verified purity with batch COA. Lab-tested research peptide for laboratory use only.
Semax is a synthetic heptapeptide analogue of the ACTH(4–7) fragment of adrenocorticotropic hormone, first developed at the Institute of Molecular Genetics in Moscow, and it has become a well-characterised subject in neuroscience research. Investigations have centred on its apparent neurotrophin-like behaviour — in particular its reported interaction with BDNF and TrkB receptor signalling, pathways studied in the context of neuronal survival and synaptic plasticity — as well as its influence on dopaminergic and serotonergic neurotransmission and on hypothalamic-pituitary-adrenal axis responses in pre-clinical models. Its ACTH-derived structure, paired with the absence of adrenocorticotropic activity, makes it a useful reference tool for laboratories studying neuropeptide pharmacology, cerebrovascular biology, and central-nervous-system peptide signalling. NutriPep supplies Semax at ≥99% verified purity with a batch Certificate of Analysis from independent lab testing, lyophilized and shipped across the EU in research-grade packaging. It is a research peptide for laboratory use only: it is not approved as a therapeutic or nootropic product for human use in most jurisdictions, is not for human consumption or injection, and should always be handled in accordance with your institution’s neuroscience-compound protocols and applicable local regulations.
| Supplier SKU | MYPXA |
| Purity | ≥99% |
| Molecular Weight | 813.92 Da |
| Molecular Formula | C₃₇H₅₁N₉O₁₀S |
| CAS Number | 80714-61-0 |
| Amino Acid Count | 7 |
| Amino Acid Sequence | MEHFPGP (Met-Glu-His-Phe-Pro-Gly-Pro) |
| Peptide Type | Synthetic ACTH(4–10) analogue (heptapeptide) |
| Appearance | White to off-white lyophilized powder |
| Solubility | Highly water-soluble. Reconstitute in bacteriostatic water or sterile saline. Clear, colourless solution. |
| Storage Instructions | Store lyophilized vials at -20°C, protected from light and humidity. Once reconstituted, store at 2–8°C and use within 7 days, or aliquot and store at -20°C for up to 3 months. Shelf life 24 months as supplied (lyophilized, -20°C). |
| Shelf Life | 24 months (lyophilized, -20°C) |
| Testing Scope | purity, endotoxins, heavy-metals, mass-spec |
| Dosagem | 10 MG, 5 MG |
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Relevância em Investigação / Research Relevance
- Investigated in models of cerebral ischaemia and neuroprotection via immunomodulatory and anti-inflammatory pathways
- Studied for its role in BDNF (brain-derived neurotrophic factor) expression and neurotrophin synthesis in neural tissue
- Examined in research contexts related to transcriptome-level gene regulation in central nervous system models
- Investigated for its structural distinction from native ACTH with regard to absence of adrenal-stimulatory activity
- Studied in preclinical models of amyloid-beta aggregation and copper-peptide interaction dynamics
Referências Científicas / Scientific References
- Semax and Pro-Gly-Pro Activate the Transcription of Neurotrophins and Their Receptor Genes after Cerebral Ischemia — Gusev EI et al. (Bulletin of Experimental Biology and Medicine, 2017)
- The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer’s Disease — Grigoriev VV et al. (Molecular and Cellular Neuroscience, 2024)
- Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models — Voskresenskaya OG et al. (ACS Chemical Neuroscience, 2021) [DOI: 10.1021/acschemneuro.1c00707]
Notas Regulamentares / Regulatory Information
Semax is not currently listed on the WADA Prohibited List. It is registered as a pharmaceutical in the Russian Federation for specific medical indications, but has not received marketing authorisation from the FDA or EMA. Regulatory status of peptides may change; researchers should verify current status. This product is sold exclusively for in-vitro research.
✓ Certificado de Análise Laboratorial (COA)
Lote testado independentemente por terceiros (Janoshik Analytical). Pureza verificada ≥99%.
For research use only. This product is intended exclusively for in-vitro research and laboratory applications. Not approved for human or animal consumption, medical treatment, or therapeutic use in the EU or US.
A Revolução dos Peptídeos na Biologia Celular
Síntese peptídica de precisão laboratorial, com certificação analítica lote a lote para investigação celular e bioquímica de rigor.
Confirmação de peso molecular exato por ESI-MS e pureza de pico garantida.
Protocolos de bancada e síntese química alinhados com as Boas Práticas de Laboratório (GLP).
Transparência total com laudos analíticos originais e cromatogramas acessíveis por lote.
Montagem automatizada de aminoácidos com proteção ortogonal para integridade biológica.
É por isso que a
Nutripep existe
Para descodificar a sinalização bioquímica que o organismo escreve a nível molecular e transformá-la em compostos peptídicos de precisão para a investigação regenerativa.
A Nutripep na vanguarda da investigação celular e bioquímica.
50+ Publicações e Ensaios · 120+ Laboratórios Parceiros · Pureza Analítica ≥ 99.4%
“A síntese de fase sólida da Nutripep estabelece um novo patamar de referência em estabilidade conformacional.”
“Eliminação rigorosa de solventes residuais e sais TFA para máxima viabilidade em ensaios in vitro.”
“O envio estéril com controlo térmico garantiu estabilidade e integridade molecular intacta até à bancada.”
“A acessibilidade imediata a laudos HPLC/MS originais por lote eleva o padrão de transparência analítica.”
“Reprodutibilidade consistente demonstrada em ensaios prolongados de proliferação celular.”
“A integridade molecular dos peptídeos Nutripep permitiu acelerar em meses as fases de ensaio pré-clínico.”

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