MOTS-C
Price range: €39,95 through €89,95
MOTS-c mitochondrial research peptide ≥99% purity, verified COA. Lab-tested peptide vials for research use only. Fast EU shipping. Order at NutriPep.eu.
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded within the mitochondrial genome — a discovery that fundamentally reframed thinking about mitochondria as purely energy-producing organelles. Since its identification, MOTS-c has been studied as a mitochondrial-derived peptide (MDP) that appears to act as a systemic signaling molecule, influencing processes beyond the mitochondria itself.
Research has investigated MOTS-c’s role in cellular energy regulation, particularly its apparent activation of AMPK — a master regulator of cellular energy homeostasis. Studies have explored how MOTS-c influences glucose metabolism, fatty acid oxidation pathways, and mitochondrial dynamics in pre-clinical models. Its ability to translocate to the nucleus under stress conditions and influence gene transcription has made it a subject of interest in mitochondrial biology and aging research.
MOTS-c research has also examined its behavior under conditions of metabolic stress, exercise physiology models, and cellular senescence, where mitochondrial signaling plays a documented role. It represents a broader research movement toward understanding how mitochondrial-derived peptides communicate with the rest of the cell and organism.
NutriPep supplies MOTS-c at ≥99% verified purity with a Certificate of Analysis from independent lab testing. Lyophilized and shipped across the EU in research-grade packaging.
What researchers should know: MOTS-c is a research peptide supplied strictly for laboratory use. It is not approved for human use and is not a therapeutic compound. Always handle in accordance with your institution’s safety and research protocols.
| Dosagem | 40 MG, 10 MG |
|---|
Relevância em Investigação / Research Relevance
- Investigated in models of mitochondrial signalling and cellular energy metabolism via AMPK pathway activation
- Studied for its role in nuclear translocation and mitochondria-to-nucleus communication
- Examined in research contexts related to the folate-AICAR-AMPK metabolic axis
- Investigated in preclinical models of age-related metabolic decline and insulin sensitivity
- Studied for its role as an exercise-responsive mitochondrial-encoded regulator in preclinical research
- Examined in models of skeletal muscle homeostasis and physical performance biomarkers
Referências Científicas / Scientific References
- The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance — Lee C et al. (Cell Metabolism, 2015) [DOI: 10.1016/j.cmet.2015.02.009]
- MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis — Kim SJ et al. (Nature Communications, 2021) [DOI: 10.1038/s41467-020-20539-3]
- MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases — Zhai D et al. (International Journal of Molecular Sciences, 2022) [DOI: 10.3390/ijms231911991]
Notas Regulamentares / Regulatory Information
MOTS-c is prohibited by WADA under Section S4.4.1 as an AMP-activated protein kinase (AMPK) activator. It is not approved for human therapeutic use by any regulatory agency. This product is sold exclusively for in-vitro research.
✓ Certificado de Análise Laboratorial (COA)
Lote testado independentemente por terceiros (Janoshik Analytical). Pureza verificada ≥99%.
For research use only. This product is intended exclusively for in-vitro research and laboratory applications. Not approved for human or animal consumption, medical treatment, or therapeutic use. MOTS-c is listed on the WADA Prohibited List as an AMPK activator.
A Revolução dos Peptídeos na Biologia Celular
Síntese peptídica de precisão laboratorial, com certificação analítica lote a lote para investigação celular e bioquímica de rigor.
Confirmação de peso molecular exato por ESI-MS e pureza de pico garantida.
Protocolos de bancada e síntese química alinhados com as Boas Práticas de Laboratório (GLP).
Transparência total com laudos analíticos originais e cromatogramas acessíveis por lote.
Montagem automatizada de aminoácidos com proteção ortogonal para integridade biológica.
É por isso que a
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Para descodificar a sinalização bioquímica que o organismo escreve a nível molecular e transformá-la em compostos peptídicos de precisão para a investigação regenerativa.
A Nutripep na vanguarda da investigação celular e bioquímica.
50+ Publicações e Ensaios · 120+ Laboratórios Parceiros · Pureza Analítica ≥ 99.4%
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