Retatrutide
Price range: €49,39 through €179,49
Retatrutide research peptide ≥99% purity, verified COA, 10 mg lyophilized vials. Laboratory research use only. Fast EU shipping at NutriPep.eu.
Retatrutide is an investigational peptide classified as a triple-agonist for its activity at three receptor targets: GLP-1R (glucagon-like peptide-1 receptor), GIPR (glucose-dependent insulinotropic polypeptide receptor), and GCGR (glucagon receptor). This triple-receptor pharmacology distinguishes it from earlier dual-agonist compounds and has made it a subject of significant interest in metabolic research.
Research into Retatrutide has focused on characterising how simultaneous agonism at all three receptor types influences metabolic signalling in pre-clinical models. Each receptor target is associated with distinct metabolic activity at the cellular and systemic level — GLP-1R and GIPR with incretin biology, and GCGR with hepatic metabolic processes. Understanding how these three pathways interact under combined agonist activity is a key question driving current research.
As a novel compound, Retatrutide research is still at a relatively early stage compared with single- or dual-agonist peptides. Pre-clinical studies have explored its receptor-binding profile, downstream signalling cascades, and comparative pharmacology against related compounds, building a growing data set for metabolic-research laboratories.
NutriPep supplies Retatrutide at ≥99% verified purity with a Certificate of Analysis from independent third-party lab testing, lyophilized and shipped across the EU in research-grade packaging.
What researchers should know: Retatrutide is an investigational research compound and is not approved for human use. It is not a pharmaceutical product in this format and is strictly for laboratory research use only — not for human consumption. Handle it in accordance with your institution’s protocols for investigational peptide compounds and all applicable local regulations.
| Dosagem | 15 MG, 30 MG, 20 MG, 10 MG, 5 MG |
|---|
Relevância em Investigação / Research Relevance
- Investigated in preclinical and clinical models of metabolic pathway modulation via triple-receptor engagement
- Studied for its role in concurrent GLP-1, GIP, and glucagon receptor activation in research settings
- Examined in Phase 2 and Phase 3 clinical research programmes (TRIUMPH) evaluating multi-agonist peptide activity
- Investigated for its distinct pharmacokinetic profile conferred by C20 fatty diacid albumin-binding conjugation
- Studied in research contexts related to body composition and metabolic biomarker analysis
Referências Científicas / Scientific References
- Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial — Jastreboff AM et al. (New England Journal of Medicine, 2023) [DOI: 10.1056/NEJMoa2301972]
- Effects of retatrutide on body composition in people with type 2 diabetes: a substudy of a phase 2 trial — Del Prete A et al. (The Lancet Diabetes & Endocrinology, 2025)
- Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the TRIUMPH registrational clinical trials — Giblin PT et al. (Diabetes, Obesity and Metabolism, 2026)
Notas Regulamentares / Regulatory Information
Retatrutide is an investigational compound currently in Phase 3 clinical trials. It has not received marketing authorisation from any regulatory agency. It is prohibited by WADA under Section S0 (Non-Approved Substances) and Section S2.4 (GLP-1 Receptor Agonists). This product is sold exclusively for in-vitro research.
✓ Certificado de Análise Laboratorial (COA)
Lote testado independentemente por terceiros (Janoshik Analytical). Pureza verificada ≥99%.
For research use only. This product is intended exclusively for in-vitro research and laboratory applications. Not approved for human or animal consumption, medical treatment, or therapeutic use. Retatrutide is an investigational compound without marketing authorisation. It is listed on the WADA Prohibited List.
A Revolução dos Peptídeos na Biologia Celular
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